Road Transportation Major interstations in the State of New Mexico are I-10, I-25 and I-40. I-10 runs on the most southern tip of the state, connecting the east and the west cost of the United States, and the border. It is a major arthery when it comes to transporting goods quickly and efficiently. I-25 runs from North to South of the state, providing access to Colorado and Mexico. I-40 is another major arthery running from the East to West through the state, it is also a major trucking road. Santa Teresa and Las Cruces, New Mexico are in Doņa Ana County, which borders El Paso County, Texas. This region is located on the western tip of Texas, approximately halfway between the Gulf of Mexico and the Pacific Ocean. This region is ideally located to serve the United States, Canada and Latin America. More, Las Cruces and Dona Ana County are ideally situated in the Southwest to solve many logistics issues. Due to its southern geographic location and temperate year-round climate, few weather-related transportation delays are experienced. Las Cruces is situated at the intersection of two major Interstate highways. Interstate-10 is a major east-west artery stretching from the southeastern U.S. to the West Coast. Interstate-10 connects to the Santa Teresa Port of Entry and Mexican Highways 2 and 45 via the Pete Domenici Highway (NM 375). Interstate-25, originating in Las Cruces, is a major north-south artery stretching to the Canadian border.