Doing business in Matamoros can be complex and difficult. Inadequate highway and crossing services can hamper commercial activity. Since few large companies have chosen to locate new facilities in Matamoros in recent years, the city's infrastructure has not kept pace with needed repairs or services.
Industrial parks on both sides of the river possess water, electricity, and gas. The price averages are as follows:

• Water- $0.015 per US gallon
• Sewage- $0.011 per US gallon
• Electricity- $0.065 per Kw / hr
• Natural Gas- $0.197 per square-meter
• LP Gas- $0.099 per liter
• Truck use- $1.50 - $2.00 per US mile

US Customs directs commercial crossing activity to the Los Indios Crossing, which is 15 - 20 miles from Brownsville. The tourist and passenger crossing into downtown Matamoros is highly congested.

Maquila employers pay State of Tamaulipas taxes in the amount of 4% - 5% of base salaries. State of Texas imposes franchise and sales taxes of 5.25% and 7.75% respectively. Brownsville local taxes on sales, real property, school, bridge, road, and college range between 3% - 4%.